Oxygen Therapy in Cyanide Poisoning

The treatment of cyanide poisoning.

Cyanide has gained historical notoriety as a poison used with intent to cause fatality. Its occurrence in industry is confined to a small number of uses in a relatively narrow range of industries, including the manufacture of Perspex and nylon and in electroplating. With proper controls in these settings, episodes of poisoning are extremely rare. However, because of the potential for a fatal ou...

Cyanide poisoning and its treatment.

Cyanide is both widely available and easily accessible throughout the world. Although the compound is not frequently encountered, it has been used as a poison and contaminant in the past and is a potential terrorist agent. Cyanide has the ability to cause significant social disruption and demands special attention to public health preparedness. It can be obtained from a variety of sources, incl...

Combined administration of hyperbaric oxygen and hydroxocobalamin improves cerebral metabolism after acute cyanide poisoning in rats.

Hyperbaric oxygen therapy (HBOT) or intravenous hydroxocobalamin (OHCob) both abolish cyanide (CN)-induced surges in interstitial brain lactate and glucose concentrations. HBOT has been shown to induce a delayed increase in whole blood CN concentrations, whereas OHCob may act as an intravascular CN scavenger. Additionally, HBOT may prevent respiratory distress and restore blood pressure during ...

Re: The treatment of cyanide poisoning.

(CWP) in the USA over the last 30 years. They then state, ‘Similar trends have been noted in Europe’. We would like to expand on this statement in respect of our experience here in the UK. In the UK coal mining industry, health surveillance (by chest X-ray) has been provided, over the last four decades, initially at 5 year, and since 1974, 4 year intervals. The prevalence of CWP among employed ...

Fatal cyanide poisoning: accidental ingestion of amygdalin.